Nano Fat

Nano Fat


For the past 20 years, plastic surgeons have used autologous fat graft to provide structural augmentation of different body regions such as the face, breasts, and buttocks. In fat grafting, intact fat cells are harvested and transferred to the target areas as tissue fillers. The fat cells stay viable and healthy after transplanted to the target areas to serve the purpose of structural augmentation.


Nanofat, on the other hand, is a different technique and is used for different purposes. In nanofat, fat cells are disintegrated and emulsified into liquid form. Nanofat contains no viable fat cells but has abundant viable adipose-derived stem cells and various growth factors released from the disintegrated fat cells. This combination of stem cells and growth factors produces positive trophic changes to the surrounding skin and tissues, including skin tone, texture, and elasticity. Since nanofat is in liquid form, it can be injected into superficial layers of the skin using a very fine needle. Unlike standard fat graft, nanofat is NOT used as tissue filler to provide structural augmentation. Instead, the primary use of nanofat is to improve the quality of the skin.


The main applications of nanofat:

  1. To improve skin changes caused by aging and sun damagesuch as skin thinning, fine wrinkle, and elasticity loss.
  2. To treat pigmentation conditions such as dark eye circle and mottled skin complexion of the face.
  3. To treat scar problems such as acne scarring, hypertrophic scar and atrophic scars.





  1. Inform the doctor of any pre-existing medical conditions and drug allergy. All medical conditions must be treated and stabilized before surgery.
  2. Stop smoking at least one week before surgery. Smoking is harmful to wound healing and increases the risks of other post-operation complications.
  3. Stop the following medications and supplements from one week before surgery until one week after surgery.
    1. All supplements containing vitamin E, ginseng, ginkgo, garlic, fish oil, and other ingredients that increase bleeding during the procedure. Other supplements, traditional medicine, and herbs, in which ingredients are unknown, have to stop as well.
    2. Medicine that increases bleeding during the procedure such as aspirin, NSAIDs, and warfarin. However, you may need to consult your physician who prescribed the medication before you stop them.
  4. On the day of surgery, wear simple and comfortable clothing. Do not wear any makeup. Do not wear any jewelry and metal objects on the face and body.





Duration: 1-2 hours

Anaesthesia: Local anaesthesia

Hospitalization: not required

Recovery*: Back to work in 1-3 days, light exercise after one week, heavy exercise after 4 weeks. *The actual speed of recovery depends on the site and extent of the fat grafting and may vary from person to person

Technique: the procedure consists of 3 steps:

  1. Fat harvest: harvesting of fat through a small opening (2-3mm), usually from the thigh or abdomen.
  2. Fat emulsification: an emulsifier turns the fat into liquid form (nanofat).
  3. Fat placement: nanofat injection into the target skin areas using a syringe with a fine needle or a special device like Hydra Needle.




Post-operative Care**

  1. What to expect: Swelling usually is very minimal.
  2. Avoid direct pressure and hot contact on the target areas.
  3. General care:
    1. Avoid smoking for at least one month. Smoking adversely affects the beneficial effects of nanofat.
    2. Adequate rest and sleep are helpful for a speedy recovery.
    3. Be relaxed and calm. Contact the clinic if there are any queries.
  4. Medicine: Finish the oral antibiotics as prescribed. Take the painkiller as prescribed when necessary.
  5. Wound care: The fine needles leave no wounds at the target areas. No dressings are required.
  6. Physical activity: Avoid heavy physical activity and exercise for at least one week.
  7. Follow-up: Come back one week after surgery for suture removal and review.
  8. Emergency: If there is heavy bleeding, a rapid increase in swelling or severe pain, immediately contact the clinic/doctor for advice.


** The instructions in this list are only for general guidance. If you have any specific queries or concerns during the post-operative recovery, please contact the clinic for further advice.


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